Brief Information of the Compound and Protein
Compound Name
2,4-diamino-5,6-disubstituted pyrimidine, 14
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PubChem ID
CID: 25129169
SID: 56453484
Canonical SMILES
Nc1nc2C(CCCCc2c(n1)N1CCNCC1)c1ccccc1
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Compound Formula C19H25N5
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q91ZY1
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 54.95 nM
   TI
   LI
   LO
   TS
2
Ki = 4.467 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 4.467 nM