Brief Information of the Compound and Protein
Compound Name
2,4-diamino-5,6-disubstituted pyrimidine, 11
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PubChem ID
CID: 25071004
SID: 56409245
Canonical SMILES
CN[C@@H]1CCN(C1)c1nc(N)nc-2c1CCCc1ccccc-21
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Compound Formula C18H23N5
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q91ZY1
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 6.607 nM
   TI
   LI
   LO
   TS
2
Ki = 5.129 nM
   TI
   LI
   LO
   TS