Brief Information of the Compound and Protein
Compound Name
14-fluoro-6-(piperazin-1-yl)-3,5-diazatricyclo[9.4.0.0^{2,7}]pentadeca-1(15),2(7),3,5,11,13-hexaen-4-amine
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PubChem ID
CID: 25128824
SID: 56453124
Canonical SMILES
Nc1nc(N2CCNCC2)c2CCCc3ccc(F)cc3-c2n1
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Compound Formula C17H20FN5
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q91ZY1
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 6.026 nM
   TI
   LI
   LO
   TS
2
Ki = 1.445 nM
   TI
   LI
   LO
   TS