Brief Information of the Compound and Protein
Compound Name
4-(2,6-Dimethoxyphenyl)-6-(4-methylpiperazin-1-yl)pyrimidin-2-ylamine
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PubChem ID
CID: 25131230
SID: 56455634
Canonical SMILES
COc1cccc(OC)c1-c1cc(N2CCN(C)CC2)nc(N)n1
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Compound Formula C17H23N5O2
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q91ZY1
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 194.98 nM
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