Brief Information of the Compound and Protein
Compound Name
3-[2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]benzonitrile
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PubChem ID
CID: 11437850
SID: 16535891
Canonical SMILES
CN1CCN(c2cc(-c3cccc(C#N)c3)nc(N)n2)CC1
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Compound Formula C16H18N6
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q91ZY1
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 234.42 nM
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