Brief Information of the Compound and Protein
Compound Name
[4-tert-Butyl-6-(4-methylpiperazin-1-yl)pyrimidin-2-yl]methylamine
    Show/Hide
PubChem ID
CID: 25130580
SID: 56454948
Canonical SMILES
CNc1nc(N2CCN(C)CC2)cc(C(C)(C)C)n1
    Show/Hide
Compound Formula C14H25N5
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
Q91ZY1
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 5128.61 nM
   TI
   LI
   LO
   TS