Brief Information of the Compound and Protein
Compound Name
2-Aminopyrimidine analog., 25
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PubChem ID
CID: 25130576
SID: 56454944
Canonical SMILES
Nc1nc(cc(n1)-c1ccc(cc1)C#N)N1CCNCC1
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Compound Formula C15H16N6
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q91ZY1
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 245.47 nM
   TI
   LI
   LO
   TS
2
Ki = 338.84 nM
   TI
   LI
   LO
   TS