Brief Information of the Compound and Protein
Compound Name
GSK554170A
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PubChem ID
CID: 56603995
Canonical SMILES
CCn1c(-c2nonc2N)nc2c(C#CC(C)(C)O)ncc(OCC3CCNCC3)c21.O=C(O)C(F)(F)F
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Compound Formula C23H28F3N7O5
Compound Structure
Protein Name
RAC-alpha serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
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AGC protein kinase AKT family
Uniprot ID
P31749
Gene Name
AKT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000218 BT-474 Homo sapiens (Human)  1
1
IC50 = 2100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10 nM