Brief Information of the Compound and Protein
| Compound Name |
4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpiperazin-1-yl)methyl]thieno[3,2-d]pyrimidin-4-yl]morpholine
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PubChem ID | |||||
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Compound Structure |
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| Protein Name |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
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Protein Classification |
Enzyme
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Transferase
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| Uniprot ID | Gene Name | PIK3CD |
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Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000013 | Sf9 | Spodoptera frugiperda (Fall armyworm) | 2 |
| 1 |
IC50 = 3 nM
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TI
LI
LO
TS
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| 2 |
Ki = 31 nM
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TI
LI
LO
TS
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Biochemical Assays
| 1 | IC50 = 3 nM | ||
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| 2 | IC50 = 4 nM | ||
| 3 | IC50 = 7 nM | ||
| 4 | IC50 = 9 nM | ||
| 5 | IC50 = 12.59 nM | ||
| 6 | IC50 = 15.7 nM | ||
| 7 | IC50 = 50.12 nM | ||
| 8 | IC50 = 75 nM | ||
| 9 | Kd = 3.3 nM | ||
| 10 | Kd = 5 nM | ||