Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2-Amino-4,5-dimethyl-thiophen-3-yl)-(3-trifluoromethyl-phenyl)-methanone
    Show/Hide
 PubChem ID
CID: 122028
SID: 14849494
Canonical SMILES
Cc1sc(N)c(C(=O)c2cccc(c2)C(F)(F)F)c1C
    Show/Hide
Compound Formula C14H12F3NOS
Compound Structure
Protein Name
 Protein Info 
Adenosine receptor A1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Nucleotide-like receptor (family A GPCR)
>
Adenosine receptor
Uniprot ID
P30542
Gene Name
ADORA1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
Kd = 1.1 nM
   TI
   LI
   LO
   TS
2
Kd = 1.8 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 13600 nM
   TI
   LI
   LO
   TS