Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-Chloro-3'-fluoro-4'-((R)-1-{[1-(2,2,2-trifluoro-acetylamino)-cyclopropanecarbonyl]-amino}-ethyl)-biphenyl-2-carboxylic acid methyl ester
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 PubChem ID
CID: 16102897
SID: 24749635
Canonical SMILES
COC(=O)c1c(Cl)cccc1-c1ccc([C@@H](C)NC(=O)C2(CC2)NC(=O)C(F)(F)F)c(F)c1
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Compound Formula C22H19ClF4N2O4
Compound Structure
Protein Name
 Protein Info 
B1 bradykinin receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Bradykinin receptor
Uniprot ID
P46663
Gene Name
BDKRB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 1.52 nM
   TI
   LI
   LO
   TS
2
Ki = 0.44 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.44 nM
2 Ki = 2 nM