Brief Information of the Compound and Protein
Compound Name
 Compound Info 
7-[2,4-bis(trifluoromethyl)phenyl]-10-methyl-2-pentan-3-yl-2,7,9-triazatricyclo[6.3.1.04,12]dodeca-1(12),3,8,10-tetraene
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 PubChem ID
CID: 44444331
Canonical SMILES
CCC(CC)n1cc2CCN(c3ccc(cc3C(F)(F)F)C(F)(F)F)c3nc(C)cc1c23
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Compound Formula C23H23F6N3
Compound Structure
Protein Name
 Protein Info 
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 125.89 nM
   TI
   LI
   LO
   TS