Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-N,N-dimethylethanamine
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 PubChem ID
CID: 6918542
SID: 14901283
Canonical SMILES
COc1ccc2n(cc(CCN(C)C)c2c1)S(=O)(=O)c1ccccc1
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Compound Formula C19H22N2O3S
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
Ki = 2 nM
   TI
   LI
   LO
   TS
2
Ki = 2.1 nM
   TI
   LI
   LO
   TS
3
Ki = 2.3 nM
   TI
   LI
   LO
   TS
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 2.3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 2 nM
2 Ki = 2.1 nM
3 Ki = 2.3 nM
4 Ki = 2.512 nM
5 Ki < 50 nM