Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-Cyano-N-{(R)-2-[4-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-piperazin-1-yl]-propyl}-N-pyridin-2-yl-benzamide
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 PubChem ID
CID: 10116877
SID: 15105537
Canonical SMILES
C[C@H](CN(C(=O)c1ccc(cc1)C#N)c1ccccn1)N1CCN(CC1)c1cccc2OCCOc12
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Compound Formula C28H29N5O3
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
IC50 = 25 nM
   TI
   LI
   LO
   TS
2
IC50 = 42 nM
   TI
   LI
   LO
   TS
3
Ki = 1.6 nM
   TI
   LI
   LO
   TS