Brief Information of the Compound and Protein
Compound Name
N-(4-chlorophenyl)-6,7-dimethoxy-2-[4-[3-(methoxymethyl)piperidin-1-yl]piperidin-1-yl]quinazolin-4-amine
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PubChem ID
CID: 44581044
Canonical SMILES
COCC1CCCN(C1)C1CCN(CC1)c1nc(Nc2ccc(Cl)cc2)c2cc(OC)c(OC)cc2n1
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Compound Formula C28H36ClN5O3
Compound Structure
Protein Name
C-C chemokine receptor type 4
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
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CC chemokine receptor
Uniprot ID
P51679
Gene Name
CCR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000795 300-19 Mus musculus (Mouse)  2
1
IC50 = 52 nM
   TI
   LI
   LO
   TS
2
IC50 = 64 nM
   TI
   LI
   LO
   TS