Brief Information of the Compound and Protein
Compound Name
1'-{4-[(4-Chlorophenyl)amino]-6,7-dimethoxyquinazolin-2-yl}-1,4'-bipiperidin-3-ol
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PubChem ID
CID: 44581042
Canonical SMILES
COc1cc2nc(nc(Nc3ccc(Cl)cc3)c2cc1OC)N1CCC(CC1)N1CCCC(O)C1
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Compound Formula C26H32ClN5O3
Compound Structure
Protein Name
C-C chemokine receptor type 4
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P51679
Gene Name
CCR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000795 300-19 Mus musculus (Mouse)  2
1
IC50 = 48 nM
   TI
   LI
   LO
   TS
2
IC50 = 85 nM
   TI
   LI
   LO
   TS