Brief Information of the Compound and Protein
Compound Name
7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one
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PubChem ID
CID: 60795
SID: 15103350
Canonical SMILES
Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl
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Compound Formula C23H27Cl2N3O2
Compound Structure
Protein Name
Potassium voltage-gated channel subfamily H member 2
Protein Classification
Ion channel
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Voltage-gated ion channel
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Potassium channels
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Voltage-gated potassium channel
Uniprot ID
Q12809
Gene Name
KCNH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 1020 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 630.96 nM
2 IC50 = 896.5 nM
3 IC50 = 3860 nM
4 IC50 < 1000 nM
5 Ki = 598 nM