Brief Information of the Compound and Protein
Compound Name
(R)-2-[1-(6,7-Dimethoxy-quinazolin-4-yl)-pyrrolidin-3-yloxy]-benzonitrile
    Show/Hide
PubChem ID
CID: 16102596
SID: 24749348
Canonical SMILES
COc1cc2ncnc(N3CC[C@H](C3)Oc3ccccc3C#N)c2cc1OC
    Show/Hide
Compound Formula C21H20N4O3
Compound Structure
Protein Name
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B
Protein Classification
Enzyme
>
Phosphodiesterase
>
Phosphodiesterase 3
>
Phosphodiesterase 3B
Uniprot ID
Q13370
Gene Name
PDE3B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
Ki < 100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki < 100 nM