Brief Information of the Compound and Protein
Compound Name
(R)-6,7-Dimethoxy-4-[3-(pyridin-2-yloxy)-pyrrolidin-1-yl]-quinazoline
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PubChem ID
CID: 16102602
SID: 24749354
Canonical SMILES
COc1cc2ncnc(N3CC[C@H](C3)Oc3ccccn3)c2cc1OC
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Compound Formula C19H20N4O3
Compound Structure
Protein Name
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B
Protein Classification
Enzyme
>
Phosphodiesterase
>
Phosphodiesterase 3
>
Phosphodiesterase 3B
Uniprot ID
Q13370
Gene Name
PDE3B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
Ki = 207 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 207 nM