Brief Information of the Compound and Protein
Compound Name
11-methyl-11,21-diazatetracyclo[12.7.0.0^{3,8}.0^{15,20}]henicosa-1(14),3(8),4,6,15,17,19-heptaene
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PubChem ID
CID: 4350931
SID: 14751316
Canonical SMILES
CN1CCc2c(Cc3ccccc3CC1)[nH]c1ccccc21
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Compound Formula C20H22N2
Compound Structure
Protein Name
D(2) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 44.5 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 19 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 41.69 nM
2 Ki = 44.5 nM
3 Ki = 44.7 nM