Brief Information of the Compound and Protein
Compound Name
(8-Chloro-10,11-dihydro-5-oxa-2,4,11-triaza-dibenzo[a,d]cyclohepten-1-yl)-(3-chloro-4-fluoro-phenyl)-amine
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PubChem ID
CID: 44409147
Canonical SMILES
Fc1ccc(Nc2ncnc3Oc4ccc(Cl)cc4CNc23)cc1Cl
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Compound Formula C17H11Cl2FN4O
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000254 DiFi Homo sapiens (Human)  1
1
IC50 = 4300 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1000 nM