Brief Information of the Compound and Protein
Compound Name
N-[4-(3-bromoanilino)-5,6-dihydropyrimido[4,5-b][1,4]benzoxazepin-8-yl]prop-2-enamide
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PubChem ID
CID: 44409153
Canonical SMILES
Brc1cccc(Nc2ncnc3Oc4ccc(NC(=O)C=C)cc4CNc23)c1
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Compound Formula C20H16BrN5O2
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000254 DiFi Homo sapiens (Human)  1
1
IC50 = 5400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5700 nM