Brief Information of the Compound and Protein
Compound Name
(3-Chloro-4-fluoro-phenyl)-(7,8-dimethoxy-10,11-dihydro-5-oxa-2,4,11-triaza-dibenzo[a,d]cyclohepten-1-yl)-amine
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PubChem ID
CID: 16046116
SID: 24432175
Canonical SMILES
COc1cc2CNc3c(Nc4ccc(F)c(Cl)c4)ncnc3Oc2cc1OC
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Compound Formula C19H16ClFN4O3
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000254 DiFi Homo sapiens (Human)  2
1
IC50 = 690 nM
   TI
   LI
   LO
   TS
2
IC50 = 700 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1200 nM