Brief Information of the Compound and Protein
Compound Name
2-((4-(5-fluoro-1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)methyl)-8-methoxy-4-propyl-3,4-dihydro-2H-benzo[b][1,4]oxazine
    Show/Hide
PubChem ID
CID: 9932697
SID: 14905647
Canonical SMILES
CCCN1CC(CN2CCC(=CC2)c2c[nH]c3ccc(F)cc23)Oc2c(OC)cccc12
    Show/Hide
Compound Formula C26H30FN3O2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 135 nM
   TI
   LI
   LO
   TS
2
Ki = 362.8 nM
   TI
   LI
   LO
   TS