Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[cyclobutyl-[4-(5-fluoro-1H-indol-3-yl)butyl]amino]-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide
    Show/Hide
 PubChem ID
CID: 11339973
SID: 16430800
Canonical SMILES
NC(=O)c1ccc(F)c2OCC(Cc12)N(CCCCc1c[nH]c2ccc(F)cc12)C1CCC1
    Show/Hide
Compound Formula C26H29F2N3O2
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 24 nM
   TI
   LI
   LO
   TS
2
Ki = 4.8 nM
   TI
   LI
   LO
   TS