Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3R)-(-)-N-Cyclobutyl-N-[3-(5-fluoro-1H-indol-3-yl)propyl]-5-methoxychroman-3-amine
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 PubChem ID
CID: 11845636
Canonical SMILES
COc1cccc2OC[C@@H](Cc12)N(CCCc1c[nH]c2ccc(F)cc12)C1CCC1
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Compound Formula C25H29FN2O2
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
IC50 = 23 nM
   TI
   LI
   LO
   TS
2
IC50 = 488 nM
   TI
   LI
   LO
   TS
3
Ki = 2.14 nM
   TI
   LI
   LO
   TS