Brief Information of the Compound and Protein
Compound Name
N-[4-chloro-2-[(1,3-dioxoisoindol-2-yl)methyl]phenyl]pyridine-2-carboxamide
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PubChem ID
CID: 11463475
SID: 16563403
Canonical SMILES
Clc1ccc(NC(=O)c2ccccn2)c(CN2C(=O)c3ccccc3C2=O)c1
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Compound Formula C21H14ClN3O3
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 245 nM
   TI
   LI
   LO
   TS
2
EC50 = 250 nM
   TI
   LI
   LO
   TS