Brief Information of the Compound and Protein
Compound Name
3-[6-(dimethylamino)-4-methylpyridin-3-yl]-6-fluoro-2,5-dimethyl-N,N-dipropylpyrazolo[1,5-a]pyrimidin-7-amine
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PubChem ID
CID: 11372928
SID: 16466171
Canonical SMILES
CCCN(CCC)c1c(F)c(C)nc2c(c(C)nn12)-c1cnc(cc1C)N(C)C
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Compound Formula C22H31FN6
Compound Structure
Protein Name
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
2
Ki = 5.6 nM
   TI
   LI
   LO
   TS