Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(cyclopropylmethyl)-3-(2,4-dichlorophenyl)-2,5-dimethyl-N-propylpyrazolo[1,5-a]pyrimidin-7-amine
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 PubChem ID
CID: 11774042
SID: 16883311
Canonical SMILES
CCCN(CC1CC1)c1cc(C)nc2c(c(C)nn12)-c1ccc(Cl)cc1Cl
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Compound Formula C21H24Cl2N4
Compound Structure
Protein Name
 Protein Info 
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
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Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
IC50 = 29 nM
   TI
   LI
   LO
   TS
2
Ki = 1.6 nM
   TI
   LI
   LO
   TS
3
Ki = 3.2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1.3 nM