Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2,5-dimethyl-3-(3-methyl-5-nitropyridin-2-yl)-N,N-dipropylpyrazolo[1,5-a]pyrimidin-7-amine
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 PubChem ID
CID: 11773483
SID: 16882736
Canonical SMILES
CCCN(CCC)c1cc(C)nc2c(c(C)nn12)-c1ncc(cc1C)[N+]([O-])=O
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Compound Formula C20H26N6O2
Compound Structure
Protein Name
 Protein Info 
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 180 nM
   TI
   LI
   LO
   TS
2
Ki = 9.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 9.1 nM