Brief Information of the Compound and Protein
Compound Name
aminothiazole, 16
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PubChem ID
CID: 10030697
SID: 15012313
Canonical SMILES
OC(=O)CCNC(=O)c1ccc(CN(c2nc(cs2)-c2ccc(cc2)C(F)(F)F)c2ccc(Cl)cc2)cc1
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Compound Formula C27H21ClF3N3O3S
Compound Structure
Protein Name
Glucagon receptor
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
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Glucagon-like receptor
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Glucagon receptor
Uniprot ID
P47871
Gene Name
GCGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000051 BHK-21 Mesocricetus auratus (Golden hamster)  2
1
IC50 = 53 nM
   TI
   LI
   LO
   TS
2
IC50 = 76 nM
   TI
   LI
   LO
   TS