Brief Information of the Compound and Protein
Compound Name
4'-(2-{[(2R)-2-Hydroxy-2-pyridin-3-ylethyl]amino}ethyl)-3-isobutyl-N-(methylsulfonyl)biphenyl-4-carboxamide Dihydrochloride
    Show/Hide
PubChem ID
CID: 42639651
SID: 81078994
Canonical SMILES
CC(C)Cc1cc(-c2ccc(CCNC[C@H](O)c3cccnc3)cc2)ccc1C(=O)NS(C)(=O)=O.Cl.Cl
    Show/Hide
Compound Formula C27H35Cl2N3O4S
Compound Structure
Protein Name
Beta-3 adrenergic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Adrenergic receptor
Uniprot ID
P13945
Gene Name
ADRB3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 0.32 nM
   TI
   LI
   LO
   TS