Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(3,5-dimethoxyphenyl)-7-methyl-1,8-naphthyridine
    Show/Hide
 PubChem ID
CID: 24873536
SID: 50128678
Canonical SMILES
COc1cc(OC)cc(c1)-c1ccc2ccc(C)nc2n1
    Show/Hide
Compound Formula C17H16N2O2
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P31424
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 51.7 nM
   TI
   LI
   LO
   TS