Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(R)-3-(3,4-dioxo-2-(1-(thiophen-2-yl)propylamino)cyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
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 PubChem ID
CID: 10272255
SID: 15277220
Canonical SMILES
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cccs1
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Compound Formula C20H21N3O4S
Compound Structure
Protein Name
 Protein Info 
C-X-C chemokine receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Chemokine receptor
>
CXC chemokine receptor
Uniprot ID
P25024
Gene Name
CXCR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 81 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 210 nM