Brief Information of the Compound and Protein
Compound Name
 Compound Info 
rac-N-(2-(2,5-dimethylpiperazin-1-yl)-4-methylquinolin-6-yl)-2-(4-(trifluoromethoxy)phenoxy)acetamide
    Show/Hide
 PubChem ID
CID: 58646147
Canonical SMILES
Cc1cc(N2C[C@@H](C)NC[C@@H]2C)nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12
    Show/Hide
Compound Formula C25H27F3N4O3
Compound Structure
Protein Name
 Protein Info 
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 3.4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 20 nM