Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(4-(3-chloro-4-fluorophenylamino)-7-(3-morpholinopropoxy)quinazolin-6-yl)acrylamide dihydrochloride
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 PubChem ID
CID: 156413
SID: 12015296
Canonical SMILES
C=CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCCCN1CCOCC1.Cl.Cl
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Compound Formula C24H27Cl3FN5O3
Compound Structure
Protein Name
 Protein Info 
Receptor tyrosine-protein kinase erbB-2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P04626
Gene Name
ERBB2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000284 MDA-MB-453
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 7.4 nM
   TI
   LI
   LO
   TS
2
IC50 = 9 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 11 nM
   TI
   LI
   LO
   TS
CL000203 T24
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 16 nM
   TI
   LI
   LO
   TS