Brief Information of the Compound and Protein
Compound Name
N-[4-(3-chloro-4-fluoroanilino)quinazolin-6-yl]-4-morpholin-4-ylbut-2-ynamide
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PubChem ID
CID: 11503073
SID: 16605010
Canonical SMILES
Fc1ccc(Nc2ncnc3ccc(NC(=O)C#CCN4CCOCC4)cc23)cc1Cl
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Compound Formula C22H19ClFN5O2
Compound Structure
Protein Name
Receptor tyrosine-protein kinase erbB-2
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase EGFR family
Uniprot ID
P04626
Gene Name
ERBB2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000284 MDA-MB-453 Homo sapiens (Human)  1
1
IC50 = 173 nM
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