Brief Information of the Compound and Protein
Compound Name
N-[4-(3-chloro-4-fluoroanilino)quinazolin-6-yl]-4-(diethylamino)but-2-ynamide
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PubChem ID
CID: 11553647
SID: 16655886
Canonical SMILES
CCN(CC)CC#CC(=O)Nc1ccc2ncnc(Nc3ccc(F)c(Cl)c3)c2c1
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Compound Formula C22H21ClFN5O
Compound Structure
Protein Name
Receptor tyrosine-protein kinase erbB-2
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase EGFR family
Uniprot ID
P04626
Gene Name
ERBB2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000284 MDA-MB-453 Homo sapiens (Human)  1
1
IC50 = 7.5 nM
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