Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-{[2-({2-[1-(propan-2-yl)pyrrolidin-2-yl]ethyl}amino)benzene]sulfonamido}-5,6,7,8-tetrahydronaphthalene-1-carboxylic acid
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 PubChem ID
CID: 11648766
SID: 16752154
Canonical SMILES
CC(C)N1CCCC1CCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O
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Compound Formula C26H35N3O4S
Compound Structure
Protein Name
 Protein Info 
Methionine aminopeptidase 2
Protein Classification
Enzyme
>
Protease
>
Metallo protease
>
Metallo protease MG clan
>
Metallo protease M24A subfamily
Uniprot ID
P50579
Gene Name
METAP2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 270 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 61.66 nM
2 IC50 = 62 nM
3 IC50 = 680 nM