Brief Information of the Compound and Protein
Compound Name
2-[(2-{[2-(dimethylamino)ethyl]amino}benzene)sulfonamido]-5,6,7,8-tetrahydronaphthalene-1-carboxylic acid
    Show/Hide
PubChem ID
CID: 11575296
SID: 16677646
Canonical SMILES
CN(C)CCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O
    Show/Hide
Compound Formula C21H27N3O4S
Compound Structure
Protein Name
Methionine aminopeptidase 2
Protein Classification
Enzyme
>
Protease
>
Metallo protease
>
Metallo protease MG clan
>
Metallo protease M24A subfamily
Uniprot ID
P50579
Gene Name
METAP2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080 Homo sapiens (Human)  1
1
EC50 = 1900 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 47.86 nM
2 IC50 <= 48 nM
3 IC50 = 560 nM