Brief Information of the Compound and Protein
Compound Name
2-[(2-{[3-(4-methylpiperazin-1-yl)propyl]amino}benzene)sulfonamido]-5,6,7,8-tetrahydronaphthalene-1-carboxylic acid
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PubChem ID
CID: 11720061
SID: 16825116
Canonical SMILES
CN1CCN(CCCNc2ccccc2S(=O)(=O)Nc2ccc3CCCCc3c2C(O)=O)CC1
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Compound Formula C25H34N4O4S
Compound Structure
Protein Name
Methionine aminopeptidase 2
Protein Classification
Enzyme
>
Protease
>
Metallo protease
>
Metallo protease MG clan
>
Metallo protease M24A subfamily
Uniprot ID
P50579
Gene Name
METAP2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080 Homo sapiens (Human)  1
1
EC50 = 400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 25.7 nM
2 IC50 = 26 nM
3 IC50 = 2100 nM