Brief Information of the Compound and Protein
Compound Name
2-({2-[(piperidin-3-ylmethyl)amino]benzene}sulfonamido)-5,6,7,8-tetrahydronaphthalene-1-carboxylic acid
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PubChem ID
CID: 11517890
SID: 16619834
Canonical SMILES
OC(=O)c1c(NS(=O)(=O)c2ccccc2NCC2CCCNC2)ccc2CCCCc12
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Compound Formula C23H29N3O4S
Compound Structure
Protein Name
Methionine aminopeptidase 2
Protein Classification
Enzyme
>
Protease
>
Metallo protease
>
Metallo protease MG clan
>
Metallo protease M24A subfamily
Uniprot ID
P50579
Gene Name
METAP2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080 Homo sapiens (Human)  1
1
EC50 = 69 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 34.67 nM
2 IC50 = 35 nM
3 IC50 = 1600 nM