Brief Information of the Compound and Protein
Compound Name
N,N-dimethyl-2-[3-[2-(trifluoromethoxy)phenyl]sulfonylindol-1-yl]ethanamine
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PubChem ID
CID: 12147017
Canonical SMILES
CN(C)CCn1cc(c2ccccc12)S(=O)(=O)c1ccccc1OC(F)(F)F
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Compound Formula C19H19F3N2O3S
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  2
1
IC50 = 792 nM
   TI
   LI
   LO
   TS
2
Ki = 16 nM
   TI
   LI
   LO
   TS