Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[4-(4-[3H]-2-cyanophenyl)piperazinyl]-N-(2,4,6-[3H]3-3-methylphenyl)acetamide derivative
    Show/Hide
 PubChem ID
CID: 11724450
SID: 16829781
Canonical SMILES
Cc1cccc(NC(=O)CN2CCN(CC2)c2ccccc2C#N)c1
    Show/Hide
Compound Formula C20H22N4O
Compound Structure
Protein Name
 Protein Info 
D(4) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P21917
Gene Name
DRD4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 7.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 2.7 nM
2 Ki = 14.5 nM