Brief Information of the Compound and Protein
Compound Name
1-[3-(2-Amino-quinolin-8-yloxy)-propyl]-3-(3-chloro-phenyl)-urea
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PubChem ID
CID: 10067783
SID: 15052996
Canonical SMILES
Nc1ccc2cccc(OCCCNC(=O)Nc3cccc(Cl)c3)c2n1
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Compound Formula C19H19ClN4O2
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000863 I3.4.2 Homo sapiens (Human)  1
1
IC50 = 0.9 nM
   TI
   LI
   LO
   TS
CL000016 IMR-32 Homo sapiens (Human)  1
1
IC50 = 8 nM
   TI
   LI
   LO
   TS