Brief Information of the Compound and Protein
Compound Name
4-[6-Methoxy-7-(3-morpholin-4-yl-propoxy)-quinazolin-4-yl]-piperazine-1-carbothioic acid (6-trifluoromethyl-pyridin-3-ylmethyl)-amide
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PubChem ID
CID: 10189022
SID: 15184509
Canonical SMILES
COc1cc2c(ncnc2cc1OCCCN1CCOCC1)N1CCN(CC1)C(=S)NCc1ccc(nc1)C(F)(F)F
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Compound Formula C28H34F3N7O3S
Compound Structure
Protein Name
Platelet-derived growth factor receptor beta
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P09619
Gene Name
PDGFRB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000197 MG-63 Homo sapiens (Human)  2
1
IC50 = 5 nM
   TI
   LI
   LO
   TS
2
IC50 = 50 nM
   TI
   LI
   LO
   TS