Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-((3S,4R)-3-(1-(2-((S)-1-amino-3-methylbutyl)-4-(trifluoromethyl)phenyl)piperazine-4-carbonyl)-4-(4-chlorophenyl)pyrrolidin-1-yl)ethanone
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 PubChem ID
CID: 44433380
Canonical SMILES
CC(C)C[C@H](N)c1cc(ccc1N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(Cl)cc1)C(C)=O)C(F)(F)F
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Compound Formula C29H36ClF3N4O2
Compound Structure
Protein Name
 Protein Info 
Melanocortin receptor 4
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Melanocortin receptor
Uniprot ID
P32245
Gene Name
MC4R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 1900 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 66 nM
   TI
   LI
   LO
   TS