Brief Information of the Compound and Protein
Compound Name
 Compound Info 
8-(4-methylphenyl)-1h-pyrrolo[2'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-7(8H)-one
    Show/Hide
 PubChem ID
CID: 16659645
SID: 26519696
Canonical SMILES
Cc1ccc(cc1)-n1cnc2c(sc3ncc4cc[nH]c4c23)c1=O
    Show/Hide
Compound Formula C18H12N4OS
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 1
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
Q13255
Gene Name
GRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 0.7 nM
   TI
   LI
   LO
   TS