Brief Information of the Compound and Protein
Compound Name
2-(2,5-difluorophenylamino)-5-isopropylthiazol-4(5H)-one
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PubChem ID
CID: 135989523
Canonical SMILES
CC(C)C1SC(Nc2cc(F)ccc2F)=NC1=O
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Compound Formula C12H12F2N2OS
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 28 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 12 nM