Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(R)-1-(3'-cyanobiphenyl-4-yl)-3-(4-fluoro-3-(trifluoromethyl)phenyl)-1-(2-(3-hydroxypyrrolidin-1-yl)ethyl)urea
    Show/Hide
 PubChem ID
CID: 11168186
SID: 16247731
Canonical SMILES
O[C@@H]1CCN(CCN(C(=O)Nc2ccc(F)c(c2)C(F)(F)F)c2ccc(cc2)-c2cccc(c2)C#N)C1
    Show/Hide
Compound Formula C27H24F4N4O2
Compound Structure
Protein Name
 Protein Info 
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 8.9 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1.8 nM
2 Ki = 8.9 nM